研究実績・活動

社会連携活動

日本公衆衛生学会・グローバル環境保健検討委員会　委員
日本衛生学会　衛生学エキスパート
日本脂質栄養学会　評議員
Int J Environ Res Public Health, Associate Editor, など

教育研究業績(著書)

地球をめぐる不都合な物質（講談社ブルーバックス, 2019, 共著）
リスク学辞典「重金属のリスク」（丸善, 2019, 共著）

教育研究業績(論文)

［最近の報告］
Tatsuta N, Asato K, Iwai-Shimada M, Iwai K, Nakayama SF, Yamazaki S, Nakai K. Dietary intake of methylmercury by 0-5 years children using the duplicate diet method in Japan. Environ Health Prev Med. 2024. (accepted)

Yaginuma-Sakurai K, Saito C, Kasahara Y, Tsuno K, Yoshimasu K, Tatsuta N, Goto M, Nakai K. Work engagement and associated factors among Japanese registered dietitians and dietitians: a cross-sectional study. Ind Health. 2024. (Online ahead of print)

Anai A, Asato K, Tatsuta N, Sakurai K, Ota C, Kuriyama S, Sugawara J, Arima T, Yaegashi N, Nakai K; Japan Environment and Children’s Study Group. Factors associated with postpartum smoking relapse at early postpartum period of Japanese women in the Japan Environmental and Children's Study. Environ Health Prev Med. 28:56. 2023.

Nakamura M, Tatsuta N, Murata K, Nakai K, Iwata T, Otobe T, Sakamoto M, Yamamoto M, Itatani M, Miura Y, Koriyama C. Neurodevelopmental associations of prenatal and postnatal methylmercury exposure among first-grade children in the Kinan region, Japan. Environ Res. 235:116688, 2023.

Tatsuta N, Asato K, Anai A, Suzuki T, Sakurai K, Ota C, Arima T, Sugawara J, Yaegashi N, Nakai K, Japan Environment and Children's Study Group. Timing of maternal smoking cessation and newborn weight, height, and head circumference. Obstet Gynecol. 141:119-125, 2023.

Sugiyama S, Momma H, Yamada A, Huang C, Tatsuta N, Sakurai K, Nakai K, Arima T, Yaegashi N, Nagatomi R. Social Capital and Physical Activity among Japanese Pregnant Women: Adjunct Study of Japan Environment and Children’s Study in Miyagi Prefecture. Tohoku J Exp Med, 259:307-318, 2023.

Tanaka K, Nishigori H, Watanabe Z, Tanoue K, Iwama N, Satoh M, Murakami T, Hoshiai T, Saito M, Mizuno S, Sakurai K, Ishikuro M, Obara T, Tatsuta N, Fujiwara I, Kuriyama S, Arima T, Nakai K, Yaegashi N, Metoki H; and the Japan Environment and Children’s Study Group. Secondhand smoke exposure is associated with the risk of hypertensive disorders of pregnancy: the Japan Environment and Children's Study. Hypertens Res. 46:834-844, 2023.

Okamoto Y, Iwai-Shimada M, Nakai K, Tatsuta N, Mori Y, Aoki A, Kojima N, Takada T, Satoh H, Jinno H. Global DNA Methylation in Cord Blood as a Biomarker for Prenatal Lead and Antimony Exposures. Toxics. 26;10:157, 2022.

Nishigori T, Obara T, Metoki H, Sakurai K, Mori M, Suzuki T, Ishikuro M, Tatsuta N, Saito M, Sugawara J, Arima T, Nakai K, Kuriyama S, Yaegashi N, Nishigori H. Validation of the Moth-er-to-Infant Bonding Scale for Infant Maltreatment by Mothers at One Month Postpartum: An Adjunct Study of the Japan Environment and Children's Study. JMA J. 5:366-369, 2022.

Niwa S, Kawabata T, Shoji K, Ogata H, Kagawa Y, Nakayama K, Yanagisawa Y, Iwamoto S, Tatsuta N, Asato K, Arima T, Yaegashi N, Nakai K. Investigation of maternal diet and FADS1 polymorphism associated with long-chain polyunsaturated fatty acid compositions in human milk. Nutrients, 14:2160, 2022.

Tatsuta N, Iwai-Shimada M, Nakayama SF, Iwama N, Metoki H, Arima T, Sakurai K, Anai A, Asato K, Kuriyama S, Sugawara J, Suzuki K, Yaegashi N, Kamijima M, Nakai K; Japan Environment and Children's Study Group. Association between whole blood metallic elements concentrations and gestational diabetes mellitus in Japanese women: The Japan environment and Children's study. Environ Res. 212(Pt B):113231, 2022.

Iwai K, Iwai-Shimada M, Asato K, Nakai K, Kobayashi Y, Nakayama SF, Tatsuta N. Intra- and Inter-Day Element Variability in Human Breast Milk: Pilot Study. 10(3):109, 2022.

Tatsuta N, Nakai K, Nakayama SF, Takeuchi A, Arima T, Yaegashi N, Kamijima M; Japan Environment and Children's Study Group, Effects of maternal exposure to lead on secondary sex ratio in Japan: The Japan Environment and Children's Study. Sci Total Environ. 817:152726, 2022.

Nishigori H, Obara T, Nishigori T, Ishikuro M, Tatsuta N, Sakurai K, Saito M, Sugawara J, Arima T, Nakai K, Mano N, Metoki H, Kuriyama S, Yaegashi N; Japan Environment and Children’s Study Group. Prenatal folic acid supplementation and autism spectrum disorder in 3-year-old offspring: the Japan environment and children's study. J Matern Fetal Neonatal Med. 2:1-10, 2021.

Sakamoto M, Haraguchi K, Tatsuta N, Nakai K, Nakamura M, Murata K. Plasma and red blood cells distribution of total mercury, inorganic mercury, and selenium in maternal and cord blood from a group of Japanese women. Environ Res. 196:110896, 2021.

Yaginuma-Sakurai K, Saito C, Kasahara Y, Tsuno K, Yoshimasu K, Tatsuta N, Goto M, Nakai K. A cross-sectional study of the association between effort-reward imbalance and psychologic distress among Japanese dietitians. J Occup Health. 63(1):e12285, 2021.

山田綾, 門間陽樹, 龍田希, 仲井邦彦, 有馬隆博, 八重樫伸生, 永富良一, エコチル調査宮城ユニットセンター, 日本人女性における妊娠・出産・育児に伴う身体活動量の経時変化とその要因：エコチル調査宮城ユニットセンターによる追加調査. 運動疫学研究. 23(1):70-83, 2021.

Kikuchi S, Kobayashi N, Watanabe Z, Ono C, Takeda T, Nishigori H, Yaegashi N, Arima T, Nakai K, Tomita H. The delivery of a placenta/fetus with high gonadal steroid production contributes to postpartum depressive symptoms. Depression Anxiety. 38(4): 422-430, 2021.

Matsumoto A, Kawabata T, Kagawa Y, Shoji K, Kimura F, Miyazawa T, Tatsuta N, Arima T, Yaegashi N, Nakai K. Associations of umbilical cord fatty acid profiles and desaturase enzyme indices with birth weight for gestational age in Japanese infants. Prostaglandins Leukot Essent Fatty Acids. 165:102233, 2021.

Tanoue K, Watanabe Z, Nishigori H, Iwama N, Satoh M, Murakami T, Tanaka K, Sasaki S, Sakurai K, Ishikuro M, Obara T, Saito M, Sugawara J, Tatsuta N, Kuriyama S, Arima T, Nakai K, Yaegashi N, Metoki H; Japan Environment and Children’s Study (JECS) Group. The prevalence of psychological distress during pregnancy in Miyagi Prefecture for 3 years after the Great Eas t Japan Earthquake. Environ Health Prev Med. 26:27, 2021.

Ishikawa T, Obara T, Nishigori H, Nishigori T, Metoki H, Ishikuro M, Tatsuta N, Mizuno S, Sakurai K, Nishijima I, Murai Y, Fujiwara I, Arima T, Nakai K, Yaegashi N, Kuriyama S, Mano N. Update on the prevalence and determinants of folic acid use in Japan evaluated with 91,538 pregnant women: the Japan Environment and Children's Study. J Matern Fetal Neonatal Med. 33:427-436, 2020.

Yaginuma-Sakurai K, Tsuno K, Yoshimasu K, Maeda T, Sano H, Goto M, Nakai K. Psychological distress and associated factors among Japanese nursery school and kindergarten teachers: a cross-sectional study. Industrial Health, 58:530-538, 2020.

Nita R, Kawabata T, Kagawa Y, Nakayama K, Yanagisawa Y, Iwamoto S, Kimura F, Miyazawa T, Tatsuta N, Arima T, Yaegashi N, Nakai K. Associations of erythrocyte fatty acid compositions with FADS1 gene polymorphism in Japanese mothers and infants. Prostaglandins Leukot Essent Fatty Acids. 152:102031, 2020.

Tatsuta N, Nakai K, Kasanuma Y, Iwai-Shimada M, Sakamoto M, Murata K, Satoh H. Prenatal and postnatal lead exposures and intellectual development among 12-year-old Japanese children. Environ Res. 189: 109844，2020.

Nishihama Y, Tatsuta N, Iwai-Shimada M, Nakai K, Arima T, Fujiwara I, Yaegashi N, Takeuchi A, Nakayama SF; Japan Environment and Children’s Study (JECS) Group. The association between gestational use of personal care products and neonatal urological abnormality at birth: The Japan Environment and Children's Study. Reprod Toxicol. 93:83-88, 2020.

Ito Y, Ueyama J, Nakayama SF, Isobe T, Oya N, Sato H, Ebara T, Yoshimasu K, Tsuno K, Tatsuta N, Nakai K, Kamijima M. Within-individual and interlaboratory variability analyses of urinary metabolites measurements of organophosphorus insecticides. J Expo Sci Environ Epidemiol. 30:721–729, 2020.

Nishigori H, Obara T, Nishigori T, Metoki H, Mizuno S, Ishikuro M, Sakurai K, Hamada H, Watanabe Z, Hoshiai T, Arima T, Nakai K, Kuriyama S, Yaegashi N; Miyagi Regional Center of Japan Environment & Children’s Study Group. Mother-to-infant bonding failure and intimate partner violence during pregnancy as risk factors for father-to-infant bonding failure at 1 month postpartum: an adjunct study of the Japan Environment & Children's Study. J Matern Fetal Neonatal Med. 33:2789-2796, 2020.

Ma C, Iwai-Shimada M, Tatsuta N, Nakai K, Isobe T, Takagi M, Nishihama Y, Nakayama, SF. Health risk assessment and source apportionment of mercury, lead, cadmium, selenium, and manganese in Japanese women: An adjunct study to the Japan Environment and Children's Study. Int J Environ Res Public Health. 17:2231, 2020.

Plouffe L, Bosson-Rieutort D, Madaniyazi L, Iwai-Shimada M, Nakai K, Tatsuta N, Nakayama SF, Verner MA. Estimated postnatal p,p'-DDT and p,p'-DDE levels and body mass index at 42 months of age in a longitudinal study of Japanese children. Environ Health. 19:49, 2020.

Nishigori H, Obara T, Nishigori T, Metoki H, Mizuno S, Ishikuro M, Sakurai K, Hamada H, Watanabe Z, Hoshiai T, Arima T, Nakai K, Kuriyama S, Yaegashi N; Miyagi Regional Center of Japan Environment & Children’s Study Group. The prevalence and risk factors for postpartum depression symptoms of fathers at one and 6 months postpartum: an adjunct study of the Japan Environment & Children's Study. J Matern Fetal Neonatal Med. 33:2797-2804, 2020.

Iwama N, Sugiyama T, Metoki H, Saito M, Hoshiai T, Watanabe Z, Tanaka K, Sasaki S, Sakurai K, Ishikuro M, Obara T, Tatsuta N, Nishigori H, Kuriyama SI, Arima T, Nakai K, Yaegashi N; Japan Environment, Children's Study Group. Associations between glycosylated hemoglobin level at less than 24 weeks of gestation and adverse pregnancy outcomes in Japan: The Japan Environment and Children's Study (JECS). Diabetes Res Clin Pract. 169:108377, 2020.

Yoshimasu K, Miyauchi N, Sato A, Yaegashi N, Nakai K, Hattori H, Arima T, Japan Environment and Children's Study Group. Assisted reproductive technologies are slightly associated with maternal lack of affection toward the newborn: The Japan Environment and Children's Study. J Obstet Gynaecol Res. 46:434-444, 2020.

［それ以前の主な報告］
Ishiyama M, Matsuo Y, Nakai N, Tatsuta N, Nakata H, Mizukawa H, Miyawaki T, Nagasaka H, Someya T, Ueno D. Temporal trends in PCB concentrations in mussels collected from areas affected by the Great East Japan Earthquake and Tsunami. Marine Pollution Bulletin. 145:81-87, 2019.

Yamada K, Kawabata T, Kagawa Y, Kimura F, Miyazawa T, Tatsuta N, Saito S, Arima T, Yaegashi N, Nakai K. Relationships between docosahexaenoic acid compositions of maternal and umbilical cord erythrocytes in pregnant Japanese women. Prostaglandins Leukot Essent Fatty Acids. 147:1-5, 2019.

Iwai-Shimada M, Kameo S, Nakai K, Yaginuma-Sakurai K, Tatsuta N, Kurokawa N, Nakayama SF, Satoh H. Exposure profile of mercury, lead, cadmium, arsenic, antimony, copper, selenium and zinc in maternal blood, cord blood and placenta: the Tohoku Study of Child Development in Japan. Environ Health Prev Med. 24:35, 2019.

Ueno D, Mizukawa H, Inanami O, Nagasaka H, Tatsuta N, Narazaki Y, Fujino T, Watanabe I, Kameda Y, Nakai K. “Caddisfly Watch”, a biomonitoring method using larvae of Stenopsyche for determining radioactive cesium contamination in rivers after the Fukushima nuclear disaster. Landscape Ecol Engineer. 14:29-35, 2018.

津野香奈美, 吉益光一, 林隆, 龍田希, 伊藤由起, 上島通浩, 仲井邦彦. 幼児向けADH行動評価尺度「行動特徴のチェックリスト（BCL）」の妥当性と信頼性の検討, 日本衛生学雑誌. 73:225-234, 2018.

Tatsuta N, Kurokawa N, Nakai K, Suzuki K, Iwai-Shimada M, Murata K, Satoh H. Effects of intrauterine exposures to polychlorinated biphenyls, methylmercury, and lead on birth weight in Japanese male and female newborns. Environ Health Prev Med. 22:39, 2017.

Tatsuta N, Murata K, Iwai-Shimada M, Yaginuma-Sakurai K, Satoh H, Nakai K. Psychomotor ability in children prenatally exposed to methylmercury: the 18-month follow-up of Tohoku Study of Child Development. Tohoku J Exp Med. 242: 1-8, 2017.

Kobayashi N, Miyauchi N, Tatsuta N, Kitamura A, Okae H, Hiura H, Sato A, Utsunomiya T, Yaegashi N, Nakai K, Arima T. Factors associated with aberrant imprint methylation and oligozoospermia. Sci Rep. 10;7:42336, 2017.

Iwai-Shimada M, Satoh H, Nakai K, Tatsuta N, Murata K, Akagi H. Methylmercury in the breast milk of Japanese mothers and lactational exposure of their infants. Chemosphere. 126:67-72, 2015.

Tatsuta N, Nakai K, Murata K, Suzuki K, Iwai-Shimada M, Kurokawa N, Hosokawa T, Satoh H. Impacts of prenatal exposures to polychlorinated biphenyls, methylmercury, and lead on intellectual ability of 42-month-old children in Japan. Environ Res. 133:321-6, 2014.

Suzuki K, Nakai K, Sugawara T, Nakamura T, Ohba T, Shimada M, Hosokawa T, Okamura K, Sakai T, Kurokawa N, Murata K, Satoh C, Satoh H. Neurobehavioral effects of prenatal exposure to methylmercury and PCBs, and seafood intake: neonatal behavioral assessment scale results of Tohoku study of child development. Environ Res. 110:699-704, 2010.

Yaginuma-Sakurai K, Murata K, Shimada M, Nakai K, Kurokawa N, Kameo S, Satoh H. Intervention study on cardiac autonomic nervous effects of methylmercury from seafood. Neurotoxicol Teratol. 32:240-245, 2010.

Sugawara N, Ohba T, Nakai K, Kakita A, Nakamura T, Suzuki K, Kameo S, Shimada M, Kurokawa N, Satoh C, Satoh H. Effects of perinatal coexposure to methylmercury and polychlorinated biphenyls on neurobehavioral development in mice. Arch Toxicol. 82: 387-97, 2008.

Nakai K, Suzuki K, Oka T, Murata K, Sakamoto M, Okamura K, Hosokawa T, Takeo S, Nakamura T, Saito Y, Kurokawa N, Kameo S, Satoh H. The Tohoku Study of Child Development: A Cohort study of effects of perinatal exposures to methylmercury and environmentally persistent organic pollutants on neurobehavioral development in Japanese children. Tohoku J Exp Med. 202: 227-237, 2004.

Nakai K, Sakuma I, Togashi H, Yoshioka M, Sugawara T, Satoh H, Kitabatake A. S-nitrosylated polyethylene glycol-conjugated hemoglobin derivative as a candidate material for oxygen therapeutics. Adv Exp Med Biol. 519:207-16, 2003.

Nakai K, Ohta T, Sakuma I, Akama H, Tokuyama S, Kobayashi Y, Takahashi TA, Kitabatake A, Nakazato Y, Sekiguchi S. Inhibition of endothelium-dependent relaxation by hemoglobin in rabbit aortic strips: Comparison between acellular hemoglobin derivatives and cellular hemoglobins. J Cardiovasc Pharmacol. 28:115-126, 1996.

Nakai K, Ward AM, Gannon M, Rifkind AB. β-Naphthoflavone induction of a cytochrome P-450 arachidonic acid epoxygenase in chick embryo liver distinct from the aryl hydrocarbon hydroxylase and from phenobarbital-induced arachidonate epoxygenase. J Biol Chem. 267:19503-19512, 1992.